2024

43. Tamal Kanti Das*; Arghya Ghosh; Zachary Grimm; Ulises Aguinaga; Muhammed Yousufuddin; László Kürti* “Organocatalytic Electrophilic Arene Amination: Rapid Synthesis of 2-Quinolones.”, Chem. Eur. J., 2024, Accepted. DOI: (10.1002/chem.202403524)

42. Agustin Mario Rodriguez Trevino; Pierre Loch-Temzelides; Sanjay Pandiri; Justin K. Kirkland; Michael T. Davenport; Ulises Aguinaga; Muhammed Yousufuddin; Daniel H. Ess; László Kürti* “Forging Structural Complexity: Diastereoselective Synthesis of Densely Substituted B-Lactams with Dual Functional Handles for Enhanced Modifications.”, Chem. Sci., 2024, 15, 14668-14676. DOI: (10.1039/D4SC01513D)

41. Alex Lin; Arghya Ghosh; Simon Yellen, Zachary T. Ball*; László Kürti* “Oxidative Nitrogen Insertion into Silyl Enol Ether C=C Bonds”, J. Am. Chem. Soc., 2024, 146, 30, 21129-21136. DOI: (10.1021/jacs.4c07111)

2023

40. Nicole Erin Behnke; Young-Do Kwon; Michael T. Davenport; Daniel H Ess; László Kürti* “Directing-Group-Free Arene C(sp2)–H Amination Using Bulky Aminium Radicals and DFT Analysis of Regioselectivity”, J. Org. Chem., 2023, 88, 11847-11854. DOI: (10.1021/acs.joc.3c01127)

39. Tamal Kanti Das; Agustin Mario Rodriguez Trevino; Sanjay N Pandiri; Sini Irvankoski; Juha H Siitonen; Sara M Rodriguez; Muhammed Yousufiddin; László Kürti* “Catalyst-Free Transfer Hydrogenation of Activated Alkenes Exploiting Isopropanol as the Sole and Traceless Reductant”, Green Chem., 2023, 25, 746-754 (DOI: 10.1039/D2GC04315G).

2022

38. Padmanabha V. Kattamuri; Jidong Zhao; Tamal K. Das, Juha H. Siitonen*, Nathan Morgan, Daniel H. Ess*, László Kürti* “Aza-Quasi-Favorskii Reaction: Construction of Highly Substituted Aziridines through a Concerted Multi-bond Rearrangement Process”, J. Am. Chem. Soc. 2022, 144, 24, 10943 (DOI: 10.1021/jacs.2c03805).

2021

37. Ana V. Serna, László Kürti*, Juha Siitonen* “Synthesis of (±)‐Setigerumine I: Biosynthetic Origins of the Elusive Racemic Papaveraceae Isoxazolidine Alkaloids”, Angew. Chem. Int. Ed. 2021, 60, 27236. (DOI: 10.1002/ange.202111049)

36. Zhe Zhou, László Kürti “Substitution‐type Electrophilic Amination Using Hydroxylamine‐Derived Reagents” in Methodologies in Amine Synthesis: Challenges and Applications, 2021, 1-30. (DOI: 10.1002/9783527826186.ch1)

35. Mahesh P. Paudyal, Mingliang Wang, Juha H. Siitonen, Yimin Hu, Muhammed Yousufuddin, Hong C. Shen, John R. Falck*, László Kürti* “Intramolecular N-Me and N-H Aminoetherification for the Synthesis of N-Unprotected 3-Amino-O-Heterocycles” Org. Biomol. Chem. 2021. Advance Article. (DOI: 10.1039/D0OB02122A)

2020

34. J. Ciciolil Hilario-Martínez, Fernando Murillo, Jair García-Méndez, Eugenia Dzib, Jesús Sandoval-Ramírez, Miguel Ángel Muñoz-Hernández, Sylvain Bernès, László Kürti, Fernanda Duarte, Gabriel Merino*, María A. Fernández-Herrera* “trans-Hydroboration–oxidation products in Δ5-steroids via a hydroboration-retro-hydroboration mechanism”, Chem. Sci. 2020, 11, 12764. (DOI: 10.1039/D0SC01701A)

33. Junliang Chang*, László Kürti* “Multi-layer 3D chirality: its enantioselective synthesis and aggregation-induced emission (AIE)”, National Science Review, 2020. (DOI: 10.1093/nsr/nwaa205)

32. Nicole Erin Behnke, Juha H. Siitonen, Stephen Chamess, László Kürti* “Synthesis of Highly-Substituted Cyclopropanes via the Quasi-Favorskii Rearrangement of α,α-Dichlorocyclobutanols”, Org. Lett. 2020, 22, 15, 5715. (DOI: 10.1021/acs.orglett.0c01229). Featured on cover of Organic Letters 15/2020.

31. Kaitlyn Lovato, Urmibhusan Bhakta, Yi Pin Ng, László Kürti* "O-Cyclopropyl Hydroxylamines: Gram-Scale Synthesis and Utility as Precursors for N-Heterocycles", Org. Biomol. Chem. 2020, 18, 3281. (DOI: 10.1039/D0OB00611D)

Table of Contents Figure for social media.png

30. Qing-Qing Cheng, Zhe Zhou, Heming Jiang, Juha H. Siitonen, Daniel H. Ess, Xinhao Zhang, László Kürti “Organocatalytic nitrogen transfer to unactivated olefins via transient oxaziridines”, Nature Catalysis, 2020, 3, 386. (DOI: 10.1038/s41929-020-0430-4) Highlighted by C&EN (link) Highligted by SynFacts (link).

Qing_Nature_Catalysis.JPG

29. Juha H. Siitonen, Sherlin Lira; Muhammed Youssufuddin, László Kürti “Total Synthesis of Isatindigotindoline C”, Org. Biomol. Chem. 2020, 18, 2051 (DOI: 10.1039/D0OB00270D).

isatindigot_website.PNG

28. Juha H. Siitonen, Padmanabha, V. Kattamuri, Muhammed Yousufuddin, László Kürti “Arylboronic Acid-Catalyzed C-Allylation of Unprotected Oximes: Total Synthesis of N-Me-Euphococcine”, Org. Lett. 2020, 22, 6, 2486. (DOI: 10.1021/acs.orglett.0c00727).

2019

27. Urmibhusan Bhakta, Padmanabha V. Kattamuri, Juha H. Siitonen, Lawrence B. Alemany, Lászlo Kürti “Highly Enantioselective Catalytic Allylboration of Ketiminoesters: Practical and Scalable Synthesis of α-Fully-Substituted Amino Esters” Org. Lett. 2019, 21, 9208-9211. (DOI: 10.1021/acs.orglett.9b03574)

26. Nicole Erin Behnke, Kaitlyn Lovato, Muhammed Yousufuddin, László Kürti “Ti‐Mediated Synthesis of Spirocyclic NH‐Azetidines from Oxime Ethers” Angew. Chem. Int. Ed. 2019, 58, 14219-14223. (DOI: 10.1002/anie.201909151)

25. Shenci Lu, Shawn Voon Hwee Ng, Kaitlyn Lovato, Jun-Yang Ong, Si Bei Poh, Xiao Qian Ng, László Kürti, Yu Zhao “Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation” Nat. Commun. 2019, 10, 3061. (DOI: 10.1038/s41467-019-10940-4)

24. Zhe Zhou, László Kürti "Electrophilic Amination: An Update" Synlett, 2019, 30, 1525-1535. (DOI: 10.1055/s-0037-1611861)

23. Padmanabha V. Kattamuri, Urmibushan Bhakta, Surached Siriwongsup, Doo-Hyun Kwon, Lawrence B. Alemany, Muhammed Yousufuddin, Daniel H. Ess, and László Kürti “Synthesis of Structurally Diverse 3-, 4-, 5- and 6-Membered Heterocycles from Diisopropyl Iminomalonates and Soft C-Nucleophiles” J. Org. Chem. 2019, 84, 7066-7099. (DOI: 10.1021/acs.joc.9b00681)

22. Lirong Guo, Fengting Liu, Liying Wang, Hairui Yuan, Lei Feng, László Kürti, and Hongyin Gao “Cascade Approach to Highly Functionalized Biaryls by a Nucleophilic Aromatic Substitution with Arylhydroxylamines” Org. Lett. 2019, 21, 2894-2898 (DOI: 10.1021/acs.orglett.9b00927)

21. Zhe Zhou, Qing-Qing Cheng, and László Kürti "Aza-Rubottom Oxidation: Synthetic Access to Primary α-Aminoketones" J. Am. Chem. Soc. 2019, 141, 2242-2246. (10.1021/jacs.8b13818)

ZZ_Aza_Rubottom.jpg

2018

20. Nicole Erin Behnke, Russell Kielawa, Doo-Hyun Kwon, Daniel H. Ess, and László Kürti "Direct Primary Amination of Alkylmetals with NH-Oxaziridine" Org. Lett. 2018, 8064-8068 (10.1021/acs.orglett.8b03734)

Nicole_Alkyl_Amination_Updated.jpg

19. Kaitlyn Lovato, Lirong Guo, Qing-Long Xu, Fengting Liu, Muhammed Yousufuddin, Daniel H. Ess,* László Kürti,* and Hongyin Gao* "Transition Metal-Free Direct Dehydrogenative Arylation of Activated C(sp3)-H Bonds: Synthetic Ambit and DFT Reactivity Predictions" Chem. Sci. 2018, 9, 7992-7999. (10.1039/C8SC02758G) Highlighted in Synfacts (link).

Chemical_Science_TBA_2018_Group_Website_Scheme.jpg

18. Zhe Zhou, Nicole Erin Behnke, László Kürti, "Copper-Catalyzed Synthesis of Hindered Ethers from α-Bromo Carbonyl Compounds" Org. Lett. 2018, 20, 5452-5456. (10.1021/acs.orglett.8b02371).

Organic_Letters_Aug_15_2018_Group_Website_Scheme.jpg

2017

17. Padmanabha V. Kattamuri, Jun Yin, Surached Siriwongsup, Doo-Hyun Kwon, Daniel H. Ess, Qun Li, Guigen Li, Muhammed Yousufuddin, Paul F. Richardson, Scott C. Sutton, László Kürti, "Practical Singly and Doubly Electrophilic Aminating Agent: A New, More Sustainable Platform for Carbon-Nitrogen Bond Formation" J. Am. Chem. Soc. 2017, (10.1021/jacs.7b05279). 

16. Zhiwei Ma, Zhe Zhou, László Kürti, "Direct and Stereospecific Synthesis of N-H and N-Alkyl Aziridines from Unactivated Olefins Using Hydroxylamine-O-Sulfonic Acids" Angew. Chem. Int. Ed. 2017, (10.1002/anie.201705530). 

15. Zhe Zhou, Zhiwei Ma, Nicole Erin Behnke, Hongyin Gao, László Kürti, "Non-Deprotonative Primary and Secondary Amination of (Hetero)Arylmetals" J. Am. Chem. Soc. 2017, 139, 115-118 (10.1021/jacs.6b12712). 

 14. Hongyin Gao, Zhe Zhou, Doo-Hyun Kwon, James Coombs, Steven Jones, Nicole Erin Behnke, Daniel H. Ess, László Kürti, "Rapid heteroatom transfer to arylmetals utilizing multifunctional reagent scaffolds." Nature Chemistry 2017, 9, 681-688. (DOI: 10.1038/NCHEM.2672). C&EN News of the Week

2016

13. Mahesh P. Paudyal, Adeniyi Michael Adebesin, Scott R. Burt, Daniel H. Ess, Zhiwei Ma, László Kürti, John R. Falck. "Dirhodium-catalyzed C-H arene amination using hydroxylamines." SCIENCE 2016, Vol 353, no 6304, p 1144-1147 (DOI: 10.1126/science.aaf8713). Highlighted by Synfacts

12. Jin-Zheng Wang, Jin Zhou, Chang Xu, Hongbin Sun*, László Kürti*, and Qing-Long Xu*. “Symmetry in Cascade Chirality-Transfer Processes: A Catalytic Atroposelective Direct Arylation Approach to BINOL Derivatives.” J. Am. Chem. Soc. 2016, 138, 5202-5205 (http://pubs.acs.org/doi/abs/10.1021/jacs.6b01458).

11. Gao, Hongyin; Xu, Qing-Long; Keene, Craig; Yousufuddin, Muhammed; Ess, Daniel H. and Kürti, László*. "Practical Organocatalytic Synthesis of Functionalized Non-C2-Symmetrical Atropisomeric Biaryls.” Angew. Chem. Int. Ed. 2016, 55, 566-571 (Hot Paper; http://onlinelibrary.wiley.com/doi/10.1002/anie.201508419/pdf).

2015 and prior

10. Kürti, László. “Streamlining Amine Synthesis” – A Perspective. SCIENCE 2015, Vol 348, no 6237, p864-865 (DOI:10.1126/science.aab2812).

9. Gao, Hongyin; Xu, Qing-Long; Keene, Craig and Kürti, László*. "Scalable, Transition-Metal-Free Direct Oxime O-Arylation: Rapid Access to O-arylhydroxylamines and Substituted Benzo[b]furans.” Chemistry – A European Journal 2014, 20, 8883-8887 (http://onlinelibrary.wiley.com/doi/10.1002/chem.201403519/pdf).

8. Wood, Ross M.; Patel, Darshan C.; Lim, Yeeun, Breitbach, Zachary S.; Gao, Hongyin; Keene, Craig; Li, Gongqiang; Kürti, László and Armstrong, Daniel W.* "Enantiomeric Separation of Biaryl Atropisomers Using Cyclofructan Based Chiral Stationary Phases.” Journal of Chromatography A 2014, 1357, 172-181 (http://www.sciencedirect.com/science/article/pii/S0021967314006700#)

7. Gao, Hongyin; Xu, Qing-Long; Ess, Daniel H. and Kürti, László*. "Transition-Metal-Free, Low-Temperature Intramolecular Amination of Aromatic C-H Bonds: Rapid Synthesis of Fused Heterocycles.” Angew. Chem. Int. Ed. 2014, 53, 2701-2705 (Hot Paper; http://onlinelibrary.wiley.com/doi/10.1002/anie.201309973/pdf). This article was featured in SYNFACTS 2014, 10(4), 0351 (https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1341004).

6. Jat, Jawahar L; Paudyal, Mahesh P.; Gao, Hongyin; Xu, Qing-Long; Yousufuddin, Muhammed.; Devarajan, Deepa; Ess, Daniel H*.; Kürti, László* and Falck, J.R.* ”Direct and Stereospecific Synthesis of Unprotected N-H and N-Me Aziridines from Olefins.” SCIENCE 2014, Vol 343, no 6166, p 61-65 (DOI:10.1126/science.1245727). This article was featured in Chemical and Engineering News on Jan 6th, 2014; C&EN Vol 92, Issue 1, p. 20-21 and in CHEMISTRY WORLD on Jan 9th, 2014; Title: “Simple route to add nitrogen to drugs”. It was highlighted as a SCIENCE Perspective. SCIENCE, 434, 33 (2014) in NATURE CHEMISTRY under the title “Protection not included” (Vol. 6, March 2014), Angew. Chem. Int. Ed.March 2014 “A Scalable Rhodium-Catalyzed Intermolecular Aziridination Reaction” and also in the blog “In the Pipeline” under the title “Easy Aziridines”.

5. Xu, Qing-Long; Gao, Hongyin; Ess, Daniel H. and Kürti, László*. "Aerobic, Transition-Metal-Free, Direct and Regiospecific Mono-a-Arylation of Ketones: Synthetic Studies and Mechanism by DFT Calculations.” J. Am. Chem. Soc. 2013, 135, 14048-14051 (http://pubs.acs.org/doi/pdf/10.1021/ja4074563).

4. Keene, Craig and Kürti, László*. "Regiospecific Synthesis of Novel Cyclic Nitrostyrenes and 3-Substituted-2-Nitronaphthalenes.” Synthesis 2013, 45(13), 1719-1729 (DOI: 10.1055/s-0033-1338867); Feature Article, Special Issue Dedicated to the 60th Birthday of Professor Scott Denmark (Jul-Aug 2013).

3. Li, Gong-Qiang; Gao, Hongyin; Keene, Craig; Devonas, Michael; Ess, Daniel H. and Kürti, László*. "Organocatalytic Aryl-Aryl Bond-Formation: An Atroposelective [3,3]-Rearrangement Approach to BINAM Derivatrives.” J. Am. Chem. Soc. 2013, 135, 7414-7417 (http://pubs.acs.org/doi/pdf/10.1021/ja401709k). This article was featured in Chem. & Eng. News on May 27th, 2013; C&EN Vol 91, Issue 21, page 40 as well as in SYNFACTS 2013, 9(9),1014 (https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1339626).

2. Gao, Hongyin; Ess, D.E.; Yousufuddin, M. and Kürti, László*. "Transition-Metal-Free Direct Arylation: Synthesis of Halogenated 2-Amino-2’-Hydroxy-1,1’-Biaryls and Mechanism by DFT Calculations.” J. Am. Chem. Soc. 2013, 135, 7086-7089 (http://pubs.acs.org/doi/pdf/10.1021/ja400897u). This article is featured on Cover of the May 15th 2013 issue of the J. Am. Chem. Soc.  (JACS). It was also featured in the May 15th, 2013 JACS Spotlights: JACS 2013, 135, 7081-7081 (dx.doi.org/10.1021/ja404575r) as well as in SYNFACTS 2013, 9(8), 0879 (DOI: 10.1055/s-0033-1339407).

1. Zhu, Chen; Li, Gongqiang; Ess, Daniel H., Falck, J.R. and Kürti, László*. "Elusive Metal-Free Primary Amination of Arylboronic Acids: Synthetic Studies and Mechanism by Density Functional Theory.” J. Am. Chem. Soc. 2012, 134, 18253-18256 (http://pubs.acs.org/doi/pdf/10.1021/ja309637r). This article was featured in Chemical and Engineering News on November 5th, 2012, p. 31. It was also Highlighted in Angewandte Chemie International Edition, April 2013 (DOI: 10.1002/anie.201300382).

Postdoctoral and Graduate Work

16. Kürti, László; Blewett, Megan M. and Corey, E.J. "The Origin of Enantioselectivity in the Jacobsen Epoxidation of Olefins." Org. Lett. 2009, 11, 4592-4595.

15. Czakó, Barbara; Kürti, László, Mammoto, Akiko, Ingber, Donald and Corey, E.J. "Discovery of Potent and Practical Antiangiogenic Agents Inspired by Cortistatin A." J. Am. Chem. Soc. 2009, 131, 9014-9019.

14. Kürti, László; Czakó, Barbara and Corey, E.J. "A Short, Scalable Synthesis of the Carbocyclic Core of the Anti-Angiogenic Cortistatins from (+)-Estrone by B-Ring Expansion." Org. Lett. 2008, 10, 5247-5250.

13. Kürti, László; Chein, Rong-Jie and Corey, E. J. "Conformational Energetics of Cationic Backbone Rearrangements in Triterpenoid Biosynthesis Provide an Insight into Enzymatic Control of Product." J. Am. Chem. Soc. 2008, 130, 9031-9036.

12. Smith, Amos B., III; Kürti, László; Davulcu, Akin H.; Cho, Young-Shin; Ohmoto, Kazuyuki. "Indole Diterpene Synthetic Studies: Development of a Second Generation Synthetic Strategy for (+)-Nodulisporic Acids A and B." J. Org. Chem. 2007, 72, 4611-4620.

11. Smith, Amos B., III; Davulcu, Akin H.; Cho, Young Shin; Kürti, László; Ishiyama, Haruaki. "Indole Diterpene Synthetic Studies. Total Synthesis of (+)-Nodulisporic Acid F and Construction of the Heptacyclic Cores of (+)-Nodulisporic Acids A and B and (-)-Nodulisporic Acid D." J. Org. Chem. 2007, 72, 4596-4610.

10. Smith, Amos B., III; Kürti, László; Davulcu, Akin H.; Cho, Young-Shin. "Development of a Scalable Synthesis of a Common Eastern Tricyclic Lactone for Construction of the Nodulisporic Acids." Org. Process Res. Dev. 2007, 11, 19-24.

9. Smith, Amos B., III; Kürti, László; Davulcu, Akin H. "A New Modular Indole Synthesis. Construction of the Highly Strained CDEF Parent Tetracycle of Nodulisporic Acids A and B." Org. Lett. 2006, 8, 2167-2170.

8. Smith, Amos B., III; Davulcu, Akin H.; Kürti, László. "Indole Diterpenoid Synthetic Studies. Construction of the Heptacyclic Core of (-)-Nodulisporic Acid D." Org. Lett. 2006, 8, 1669-1672.

7. Smith, Amos B., III; Davulcu, Akin H.; Kürti, László. "Indole Diterpenoid Synthetic Studies. The Total Synthesis of (+)-Nodulisporic Acid F." Org. Lett. (2006), 8, 1665-1668.

6. Harmata, Michael; Bohnert, Gary; Kürti, László; Barnes, Charles L. "Intramolecular 4+3 cycloadditions. A cyclohexenyl cation, its halogenated congener and a quasi-Favorskii rearrangement." Tetrahedron Lett. 2002, 43, 2347-2349.

5. Harmata, Michael; Barnes, Charles L.; Brackley, James; Bohnert, Gary; Kirchhoefer, Patrick; Kürti, László; Rashatasakhon, Paitoon. "Generation of Cyclopentadienones from 2-Bromocyclopentenones." J. Org. Chem. 2001, 66, 5232-5236.

4. Juhász, László; Kürti, László; Antus, Sándor. "Simple Synthesis of Benzofuranoid Neolignans from Myristica fragrans." J. Nat. Prod.  2000, 63, 866-870.

3. Kürti, László; Szilágyi, László; Antus, Sándor; Nógrádi, Mihály. "Oxidation of 2-methoxyphenols with a hypervalent iodine reagent. Improved synthesis of asatone and demethoxyasatone." Eur. J. Org. Chem.  1999, 10, 2579-2581.

2. Kürti, László; Herczegh, Pál; Visy, Júlia; Simonyi, Miklós; Antus, Sándor; Pelter, Andrew. "New insights into the mechanism of phenolic oxidation with phenyliodonium(III) reagents." J. Chem. Soc., Perkin Trans. 1 1999, 4, 379-380.

1. Harmata, Michael; Shao, Lixin; Kürti, László; Abeywardane, Asitha. "[4+3] Cycloaddition reactions of halogen-substituted cyclohexenyl oxyallylic cations." Tetrahedron Lett.  1999, 40, 1075-1078.