Dr. Zhiwei Ma has taken a position of Research Investigator at the Genomic Institute of Novartis Research Foundation (GNF) in San Diego, CA. Congratulations and best wishes!
Group members Dr. Zhe Zhou, Miss Nicole Behnke and Miss Kaitlyn Lovato presented their research at the 18th Tetrahedron Symposium in Budapest, Hungary. Professor Kürti was a invited keynote speaker for this high profile conference and gave a talk on the group's research.
Graduate student Miss Kaitlyn Lovato was awarded the prestigious NSF Graduate Research Fellowship (September 1st 2017 - September 1st 2020).
Undergraduate student Mr. James Siriwongsup was awarded the George Holmes Richter Fellowship in Chemistry, a 10-week fellowship in support of undergraduate chemistry summer research.
Undergraduate student Mr. Russell Kielawa was awarded the Zevi & Bertha Salsburg Memorial Fellowship in Chemistry.
Congratulations to Kaitlyn, James and Russell!
Rice News highlighted two of our recent publications. Congratulations to Venkatesh, Zhiwei, Zhe, Jun and James! Special thanks to Mr. James Siriwongsup, who contributed a lot to a high impact project as an undergraduate student!
Dr. Kattamuri's recent JACS paper has been highlighted by C&EN! This project is a collaboration between the Kürti group at Rice, the Ess group at Birgham Young and the Li group at Nanjing University/Texas Tech. The newly developed method can make secondary aryl amines without the use of transition-metal catalysis.
Learn more at: http://cen.acs.org/articles/95/i28/Arylamines-made-easy.html
The Rice lab of synthetic chemist László Kürti reported its success at creating highly efficient aminating and hydroxylating reagents from abundant and biorenewable terpenoids that promises to make the reagents' use environmentally friendly and cost-effective.
Read the abstract at http://dx.doi.org/10.1038/nchem.2672
News release can be found online at http://news.rice.edu/2016/11/28/pine-product-offers-fresh-take-on-fine-chemical-synthesis/
Primary and N-alkyl arylamine motifs are key functional groups in pharmaceuticals, agrochemicals, and functional materials, as well as in bioactive natural products. However, there is a dearth of generally applicable methods for the direct replacement of aryl hydrogens with NH2/NH(alkyl) moieties. Here, we present a mild dirhodium-catalyzed C-H amination for conversion of structurally diverse monocyclic and fused aromatics to the corresponding primary and N-alkyl arylamines using NH2/NH(alkyl)-O-(sulfonyl)hydroxylamines as aminating agents; the relatively weak RSO2O-N bond functions as an internal oxidant. The methodology is operationally simple, scalable, and fast at or below ambient temperature, furnishing arylamines in moderate-to-good yields and with good regioselectivity. It can be readily extended to the synthesis of fused N-heterocycles. (Link to the article: DOI: 10.1126/science.aaf8713)
See press release here: http://news.rice.edu/2016/09/12/chemists-make-strides-to-simplify-drug-design-and-synthesis/
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